Biopharmaceutics modeling and simulations [electronic resource] : theory, practice, methods, and applications / Kiyohiko Sugano.
By: Sugano, Kiyohiko.
Contributor(s): ebrary, Inc.
Material type:
BookPublisher: Hoboken, N.J. : Wiley, c2012Description: xxxv, 483 p. : ill.Subject(s): Biopharmaceutics -- Simulation methods | Computer simulationGenre/Form: Electronic books.DDC classification: 615.7 Online resources: An electronic book accessible through the World Wide Web; click to view | Item type | Current location | Collection | Call number | URL | Copy number | Status | Date due | Item holds |
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E-book
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IUKL Library | Subscripti | http://site.ebrary.com/lib/kliuc/Doc?id=10583403 | 1 | Available |
Includes bibliographical references and index.
Introduction -- Theoretical framework I : solubility -- Theoretical framework II : dissolution -- Theoretical framework III : biological membrane permeation -- Theoretical framework IV : gastrointestinal transit models and integration -- Physiology of gastrointestinal tract and other administration sites in humans and animals -- Drug parameters -- Validation of mechanistic models -- Bioequivalence and biopharmaceutical classification system -- Dose and particle size dependency -- Enabling formulations -- Food effect -- Biopharmaceutical modeling for miscellaneous cases -- Intestinal transporters -- Strategy in drug discovery and development -- Epistemology of biopharmaceutical modeling and good simulation practice.
Electronic reproduction. Palo Alto, Calif. : ebrary, 2011. Available via World Wide Web. Access may be limited to ebrary affiliated libraries.
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