On Protein Structure, Function and Modularity from an Evolutionary Perspective.
By: Pilst�al, Robert.
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Intro -- Abstract -- Acknowledgments -- Author Contributions -- Contents -- List of Figures -- Abbreviations -- Introduction -- What is Science? -- Life and its Molecules -- Proteins - order and disorder -- Systems -- Thesis -- Method -- Alignments -- Contact prediction -- Structure prediction -- Dynamics simulation -- Clustering analysis -- Essential Dynamics Analysis -- Graphs and Structures -- Allosteric Network Analysis -- Ensemble Quality Assessment -- Present Investigations -- Function in transiently ordered islets of intrinsically disordered proteins (Paper I) -- Functional analysis of protein structure dynamics using graph models and multivariate statistics (Paper II) -- Improvements in Protein Model Quality Assessment from Automated Domain Partitioning using Spectral Clustering (Paper III and Manuscript I) -- Functional Interaction Network of c-MYC Conserved Regions determined by Evolutionary Couplings (Manuscript II) -- Conclusion -- Future Perspectives -- Bibliography -- Paper I -- Paper II -- Paper III -- Manuscript I -- Manuscript II.
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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2023. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
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