Intro -- Preface -- Acknowledgment -- Contents -- Part I: Symposium I: Biomaterials in Interface Science -- Chapter 1: Low-Modulus Ti Alloys Suitable for Rods in Spinal Fixation Devices -- 1.1 Introduction -- 1.2 Mechanism of Increasing Young's Modulus in Deformed Region -- 1.3 Possible Alloy System -- 1.4 Ti-Mo Alloys -- 1.4.1 Microstructures Before and After Deformation -- 1.4.2 Young's Modulus Change by Deformation -- 1.4.3 Deformation-Induced Products and Phase Constitutions -- 1.4.4 Springback -- 1.5 Ti-Cr Alloys -- 1.5.1 Microstructures Before and After Deformation -- 1.5.2 Young's Modulus Change by Deformation -- 1.5.3 Deformation-Induced Products and Phase Constitutions -- 1.5.4 Springback -- 1.6 Young's Modulus Under Solution Treatment Conditions and Increment Ratio of Young's Modulus by Cold Rolling -- 1.7 Toward Practical Applications -- 1.8 Summary -- References -- Chapter 2: Ceramic Coating of Ti and Its Alloys Using Dry Processes for Biomedical Applications -- 2.1 Introduction -- 2.2 Antibacterial Properties of Ag-Containing Amorphous Calcium Phosphate Coating Films -- 2.3 Photocatalytic Activity of TiO2 Layers Formed by Two-­Step Thermal Oxidation -- 2.3.1 UV (Ultraviolet) Response -- 2.3.2 Visible-Light Response -- 2.4 Summary -- References -- Chapter 3: Dealloying Toxic Ni from SUS316L Surface -- 3.1 Introduction -- 3.1.1 Dealloying in a Metallic Melt -- 3.1.2 Reaction Design for Dealloying Ni from SUS316L -- 3.2 Experimental Procedure -- 3.3 Results and Discussion -- 3.3.1 Dealloying Ni Treatments -- 3.3.2 Polarization Tests -- 3.3.3 Ion Release Tests -- 3.4 Conclusions -- References -- Chapter 4: Bio-ceramic Coating of Ca-Ti-O System Compound by Laser Chemical Vapor Deposition -- 4.1 Introduction -- 4.2 Laser Chemical Vapor Deposition -- 4.3 Bio-ceramic Coating of Ca-Ti-O by Laser CVD [25, 26] -- 4.4 Summary -- References.

Part II: Symposium II: Innovation for Oral Science and Application -- Chapter 5: Development of a Robot-Assisted Surgery System for Cranio-Maxillofacial Surgery -- 5.1 General Information of Surgical Robots -- 5.2 Computer-Aided Design (CAD) System for CMF Surgery -- 5.3 Surgical Robot for CMF Surgery -- 5.3.1 Conformation of the Robotic System -- 5.3.2 Safety Control of the Robotic System -- 5.3.3 Navigation and Trail Program -- 5.3.4 Test of the Robot -- 5.4 Medical Experiment for the Robotic System -- 5.4.1 Evaluation of the CAD Software -- 5.4.2 Accuracy of the Three-Dimensional Reconstruction of the CAD Software -- 5.4.3 Accuracy of the Navigation System -- 5.4.4 Animal Experiment of Robot-Assisted Operations -- References -- Chapter 6: Facilitating the Movement of Qualified Dental Graduates to Provide Dental Services Across ASEAN Member States -- 6.1 Formation of ASEAN to AJCCD -- 6.2 MRA for Free Flow of Services and Professionals -- 6.3 Impact on Dental Education -- 6.4 Facilitating Free Movement of Dental Professionals Across ASEAN -- 6.4.1 Current Work -- 6.4.2 Future Work -- 6.5 Conclusion -- References -- Chapter 7: Putting the Mouth into Health: The Importance of Oral Health for General Health -- 7.1 Introduvction -- 7.2 The Oral-Systemic Nexus -- 7.3 Oral-Systemic Health Associations -- 7.4 The Oral Environment: A Model for Other Body Systems -- 7.5 Summary -- References -- Chapter 8: Orofacial Stem Cells for Cell-Based Therapies of Local and Systemic Diseases -- 8.1 Overview -- 8.1.1 Need for Stem/Progenitor Cell-Based Therapy -- 8.1.2 Cell Sources During Orofacial Development -- 8.2 Mesenchymal Stem Cell-Derived Oral Tissues -- 8.2.1 Markers and Sources of Orofacial MSCs -- 8.2.2 Mesenchymal Stem Cells of Dental Pulp Stem Cells (DPSCs) -- 8.2.3 MSCs of the Periodontal Ligament, Apical Papilla and Follicles -- 8.3 Muscle Stem Cells.

8.3.1 Potential of Orofacial Muscle Stem Cells in Cardiac Repair -- 8.3.2 Developmental Similarities of Cardiac and Orofacial Myogenic Progenitors -- 8.3.3 An Interesting Example of Using Tongue Stem Cell for Cardiac Repair -- 8.4 Closing Remark -- References -- Chapter 9: Biomaterials in Caries Prevention and Treatment -- 9.1 Synthesis of Novel Mineralization Materials in Preventive Dentistry -- 9.2 Quaternary Ammonium Methacrylates (QAMs) -- 9.2.1 Killing Bacteria and Inhibiting Biofilms -- 9.2.2 Mechanical Properties -- 9.2.3 Durability -- 9.2.4 Biological Safety -- 9.2.5 Inhibiting MMPs -- 9.2.6 Mechanism -- 9.2.7 Resistant/Persister Bacteria -- 9.2.8 Models -- References -- Part III: Symposium III: Regenerative Oral Science -- Chapter 10: Efficacy of Calcium Phosphate-Based Scaffold Materials on Mineralized and  Non-­mineralized Tissue Regeneration -- 10.1 Introduction -- 10.2 Mineralized and Non-mineralized Tissue Responses -- 10.3 Matrix Materials for Calcium Phosphate -- 10.4 Cell Responses to Calcium Phosphate Materials -- 10.5 Conclusion -- References -- Chapter 11: Gene Delivery and Expression Systems in Induced Pluripotent Stem Cells -- 11.1 Introduction -- 11.2 Viral-Based Gene Delivery Systems -- 11.2.1 Adenovirus Vectors -- 11.2.2 AAV Vectors -- 11.2.3 Retrovirus Vectors -- 11.2.4 Lentivirus Vectors -- 11.3 Transposon-Based Gene Delivery Systems -- 11.4 tet-Controlled Transcriptional Regulation System -- 11.5 Conclusions -- References -- Chapter 12: Emerging Regenerative Approaches for Periodontal Regeneration: The Future Perspective of Cytokine Therapy and Stem Cell Therapy -- 12.1 Introduction -- 12.2 Periodontal Ligament as a Storage Site for Periodontal Tissue Stem Cells -- 12.3 Concept and Current Status of Periodontal Tissue Regenerative Therapy -- 12.4 Possibility of Cytokine Therapy.

12.5 Inducing Periodontal Tissue Regeneration with Basic Fibroblast Growth Factor (FGF-2) -- 12.6 Future Outlook of Cytokine Therapy Using FGF-2 -- 12.7 Possibility of Periodontal Tissue Regenerative Therapy with Stem Cell Transplantation -- 12.8 Conclusion -- References -- Chapter 13: Molecular Mechanisms Regulating Tooth Number -- 13.1 Introduction -- 13.2 Skin Appendage -- 13.3 Missing Teeth -- 13.3.1 Missing Teeth in Humans -- 13.3.1.1 Non-syndromic (Isolated) Familial Missing Teeth -- 13.3.1.2 Syndromic Missing Teeth -- 13.3.1.3 Sporadic Missing Teeth -- 13.3.2 Missing Teeth in Mice -- 13.4 Supernumerary Teeth -- 13.4.1 Supernumerary Teeth in Humans -- 13.4.1.1 Syndromic Extra Teeth in Humans -- 13.4.1.2 Missing and Extra Teeth in Humans -- 13.4.2 Supernumerary Teeth in Mice -- 13.5 Odontogenic Activity Between Tooth Germs -- 13.6 Tooth Initiation and Tooth Type -- 13.7 The Midline and Tooth Development -- 13.8 Conclusion -- References -- Part IV: Symposium IV: Medical Device Innovation for Diagnosis and Treatment of Biosis- Abiosis Interface -- Chapter 14: Open-Source Technologies and Workflows in Digital Dentistry -- 14.1 Cloud Base Solution for Intelligent Dental Clinic and Manufacturing System -- 14.2 Integration of Digital Information -- 14.3 A Shade Guide Development Based on Open-Source Technology -- 14.4 3D Printing Applications in Digital Dentistry -- 14.5 Conclusions -- References -- Chapter 15: Detection of Early Caries by Laser-Induced Breakdown Spectroscopy -- 15.1 Introduction -- 15.2 Experimental Setup -- 15.3 Results and Discussion -- 15.4 Conclusion -- References -- Chapter 16: Acoustic Diagnosis Device for Dentistry -- 16.1 Introduction -- 16.2 Materials and Methods -- 16.2.1 Observation of Rat Periodontal Ligament Using Scanning Acoustic Microscopy -- 16.2.1.1 Scanning Acoustic Microscope (SAM) -- 16.2.1.2 Tissue Preparation.

16.2.1.3 Image Analysis -- 16.2.1.4 Statistics -- 16.2.2 Observation of Human Carious Dentin Using Acoustic Impedance Microscopy -- 16.2.2.1 Acoustic Impedance Microscope (AIM) -- 16.2.2.2 Tissue Preparation -- 16.2.2.3 Scanning Electron Microscopy (SEM) -- 16.2.2.4 Statistics -- 16.2.3 Portable Acoustic Stiffness Checker (PASC) -- 16.3 Results -- 16.3.1 SAM Observation of PDL -- 16.3.2 Sound Speed Analysis -- 16.3.2.1 AIM Observation of Dentin Caries -- 16.3.2.2 SEM Observation of Dentin Caries -- 16.3.3 Ultrasound Stiffness Checker -- 16.4 Discussion -- 16.4.1 SAM Observation of PDL -- 16.4.2 AIM Observation of Dentin Caries -- References -- Part V: Poster Presentation Award Winners -- Chapter 17: Activation of TLR3 Enhance Stemness and Immunomodulatory Properties of Periodontal Ligament Stem Cells (PDLSCs) -- 17.1 Introduction -- 17.2 Materials and Methods -- 17.2.1 PDLSC Culture -- 17.2.2 Poly(I:C) Treatment -- 17.2.3 Mineralization Assay -- 17.2.4 Gene Expression Analysis -- 17.2.5 Flow Cytometry -- 17.2.6 Statistical Analyses -- 17.3 Results and Discussion -- 17.4 TLR3 Activation Promote Stemness of PDLSCs -- 17.5 TLR3 Activation Enhance Immunosuppressive Properties of PDLSCs -- 17.6 TLR3 Activation Induces IFN(Sd(B Production in PDLSCs Via NF-kB Pathway -- 17.7 Conclusion -- References -- Chapter 18: Influence of Exogenous IL-12 on Human Periodontal Ligament Cells -- 18.1 Introduction -- 18.2 Materials and Methods -- 18.2.1 Cell Culture -- 18.2.2 Application of IL-12, IFN(Sd(B, IL-1(Sb(B, and TNF(Sa(B -- 18.2.3 Reverse Transcription-Polymerase Chain Reaction (RT-PCR) -- 18.2.4 Real-Time Polymerase Chain Reaction (Real-Time PCR) -- 18.2.5 Statistical Analyses -- 18.3 Results and Discussions -- 18.3.1 Expressions of IL-12 and IL-12 Receptor in Periodontal Tissue Increased During Periodontal Inflammation.

18.3.2 IL-12-Mediated IFN(Sd(B Expression in hPDL Cells via STAT4 and NF-kB Signaling Pathways.

Description based on publisher supplied metadata and other sources.

Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2023. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.