000 04324nam a22003494a 4500
001 ebr10304694
003 CaPaEBR
007 cr cn|||||||||
008 041115s2005 njua sfb 001 0 eng
010 _z 2004027077
020 _z0471213845 (cloth)
040 _aCaPaEBR
_cCaPaEBR
035 _a(OCoLC)609350479
050 1 4 _aRM301.25
_b.D784 2005eb
082 0 4 _a615/.19
_222
245 0 0 _aDrug discovery handbook
_h[electronic resource] /
_cedited by Shayne Cox Gad.
260 _aHoboken, N.J. :
_bWiley-Interscience,
_cc2005.
300 _axix, 1471 p. :
_bill.
504 _aIncludes bibliographical references and index.
505 0 _aDrug discovery in the 21st century: an introduction / Shayne C. Gad -- Natural products / Charles B. Spainhour -- Cancer cell proteomics using molecular aptamers / Weihong Tan, Zehui Cao, Dihua Shangguang -- Molecular similarity methods and QSAR models as tools for virtual screening / J�urgen Bajorath -- Systems biology: applications in drug discovery / Sean Ekins ...[et al.] -- High throughput flow cytometry / Larry A. Sklar ... [et al.] -- Combining NMR spectral information with associated structural features to form computationally non-intensive, rugged, and objective models of biological activity / Richard Beger, Dan A. Buzatu, Jon G. Wilkes -- Using Microsoft Excel as a laboratory data management tool / A. Erik Rubin, Mark F. Russo, William Neil -- The age of regulation / Sandy Weinberg, Gerald J. Whartenby -- Simultaneous screening of multiple cell lines using the CellCardtm system / Oren E. Beske -- Protein x-ray crystallography in drug discovery / Peter Nollert ...[et al.] -- Biological and chemistry assays available during drug discovery and developability assessment / Duane B. Lakings -- Strategies and methods in monitoring and targeting protein-protein interactions / Arianna Loregian, Giorgio Pal�u -- High throughput screening: evolution of technology and methods -- Martyn N. Banks ... [et al.] -- Metal-enhanced fluorescence: application to high-throughput screening and drug discovery / Kadir Aslan .. [et al,] -- Methods for the design and analysis of replicate-experiment studies to establish assay reproducibility and the equivalence of two potency assays / Brian J. Eastwood ... [et al.] -- Coupled luminescent methods in drug discovery: three-minute assays for cytotoxicity and phosphatase activity / Michael J. Corey, Robert J. Kinders -- Design and pharmaceutical applications of prodrugs / Tomi Jarvinen ... [et al.] -- GABA and glutamate receptor ligands and their therapeutic potential in CNS disorders / Ulf Madsen ... [et al.] -- Cardiac sarcolemmal ATP-sensitive potassium channel antagonists: novel ischemia-selective antiarrhythmic agents / George E. Billman -- Factors influencing the efficacy of mediator-specific anti-inflammatory, glucocorticoid and anti-coagulant therapies for sepsis / Peter C. Minneci ... [et al.] -- Combinatorial chemistry in the drug discovery process / Nathan T. Ross, Brian R. McNaughton, Benjamin L. Miller -- Herbal medicines and animal models of gastrointestinal diseases / C.H. Cho, J.K.S. Ko -- Endocrine and metabolic agents / Brian L. Furman -- Respiratory viruses / Paul D. Olivo -- Strategies in the design of antiviral drugs / Erik De Clercq, Piet Herdewijn -- Protein kinase inhibitors in drug discovery / Keykavous Parang, Gongqin Sun -- RNA-based therapies / Ingmar Hoerr, Steve Pascolo -- Novel imaging agents for molecular MR imaging of cancer / Dmitri Artemov, Zaver M. Bhujwalla -- Genomics-based drug discovery / Spyro Mousses -- Cancer drug discovery / Susan Mooberry.
533 _aElectronic reproduction.
_bPalo Alto, Calif. :
_cebrary,
_d2013.
_nAvailable via World Wide Web.
_nAccess may be limited to ebrary affiliated libraries.
650 0 _aDrugs
_xResearch
_vHandbooks, manuals, etc.
650 0 _aDrug development
_vHandbooks, manuals, etc.
650 0 _aDrugs
_xDesign
_vHandbooks, manuals, etc.
650 0 _aPharmaceutical chemistry
_vHandbooks, manuals, etc.
655 7 _aElectronic books.
_2local
700 1 _aGad, Shayne C.,
_d1948-
710 2 _aebrary, Inc.
856 4 0 _uhttp://site.ebrary.com/lib/kliuc/Doc?id=10304694
_zAn electronic book accessible through the World Wide Web; click to view
942 _2lcc
_cEBK
999 _c156348
_d156348