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05947nam a22004693i 4500 |
| 001 - CONTROL NUMBER |
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EBC7141534 |
| 003 - CONTROL NUMBER IDENTIFIER |
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MiAaPQ |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20240322153007.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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231028s2022 xx o ||||0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783031118142 |
| Qualifying information |
(electronic bk.) |
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| Cancelled/invalid ISBN |
9783031118135 |
| 035 ## - SYSTEM CONTROL NUMBER |
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| System control number |
(MiAaPQ)EBC7141534 |
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| System control number |
(Au-PeEL)EBL7141534 |
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| System control number |
(OCoLC)1354208094 |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
MiAaPQ |
| Language of cataloging |
eng |
| Description conventions |
rda |
| -- |
pn |
| Transcribing agency |
MiAaPQ |
| Modifying agency |
MiAaPQ |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
RA410-410.9 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Canci, Jung Kyu. |
| 245 10 - TITLE STATEMENT |
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| Title |
Quantitative Models in Life Science Business : |
| Remainder of title |
From Value Creation to Business Processes. |
| 250 ## - EDITION STATEMENT |
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| Edition statement |
1st ed. |
| 264 #1 - |
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Cham : |
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Springer International Publishing AG, |
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2022. |
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| -- |
�2023. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
1 online resource (131 pages) |
| 336 ## - |
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text |
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txt |
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rdacontent |
| 337 ## - |
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computer |
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c |
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rdamedia |
| 338 ## - |
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online resource |
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cr |
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rdacarrier |
| 490 1# - SERIES STATEMENT |
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| Series statement |
SpringerBriefs in Economics Series |
| 505 0# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Intro -- Preface -- Acknowledgments -- Contents -- *-1pc Value Creation and Managing Intellectual Property in the Life Science Industry -- Value Creation, Valuation and Business Models in the Pharmaceutical Sector -- 1 Value Principles in the Pharmaceutical Industry -- 2 Value Creation in the Pharmaceutical Industry -- 3 `Keeping Focus': The Traditional Value Token -- 4 `Extending Horizons': Innovation-Integration Across the Value Chain -- 5 Value Protection: Intellectual Property in the Life Sciences -- 5.1 Patent Evaluation -- 6 Modelling the Patent Value as a Stochastic Process -- 6.1 The Patent Life Model -- 6.2 Viewing a Generic Case -- 6.3 Interferon Beta 1a: A Real-World Case -- 7 The Future of Value and Valuation in Pharma -- References -- Limited Commercial Licensing Strategies: A Piecewise Deterministic Differential Game -- 1 Limited Commercial Licenses in the Pharmaceutical Industry -- 1.1 Probability of Issuing a CL -- 2 A Differential Game of Limited Commercial Licensing -- 2.1 Preliminaries -- 2.2 Profits and Sales in Each Regime -- 2.3 Switching Between Stages -- 2.4 The Problem -- 3 Solving the Model -- 4 Perspective -- References -- Partnership Models for R& -- D in the Pharmaceutical Industry -- 1 Introduction -- 2 The Problem of R& -- D Efficiency of Pharmaceutical Companies -- 2.1 Eroom's Law -- 2.2 Analysis of R& -- D Costs in the Pharmaceutical Sector -- 2.3 Analysis of Pipeline Drugs -- 3 New R& -- D Open Innovation Models for Pharmaceutical Companies -- 3.1 Mergers and Acquisitions -- 3.2 In-licensing Agreements -- 3.3 Outsourcing R& -- D Processes from CROs -- 3.4 R& -- D Collaborations -- 3.5 Public-Private Partnerships -- 3.6 Crowdsourcing -- 3.7 Innovation Centers -- 3.8 Open Source -- References -- *-1pc Modelling Specific Business Processes in the Life Science Industry. |
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| Formatted contents note |
Pharma Tender Processes: Modeling Auction Outcomes -- 1 Introduction -- 2 Pharmaceutical Tendering -- 2.1 Pharmaceutical Tendering Mechanism in Different Countries -- 2.2 Effect of Pharmaceutical Tendering -- 3 Tendering as Auction: Scope and Concept -- 3.1 Tender Versus Auction -- 3.2 Independent Private Value Auction -- 3.3 First Price Sealed Auction -- 3.4 Number of Bidders -- 4 Empirical Methods for Price Auction Estimation -- 4.1 Bidding Price Determinants Estimation with Reduced Form Approach -- 4.2 Structural Estimation of Auction Models -- 4.3 Quantile-Based Non-parametric Estimation of Private Value -- 5 Non-parametric Estimation on Observational Data -- 5.1 Dataset -- 5.2 Visualization and Descriptive Analysis -- 5.3 Assumptions Validation -- 5.4 Modeling and Estimation -- 5.5 Adjustments and Lessons Learned -- References -- Multi-Echelon Inventory Optimization Using Deep Reinforcement Learning -- 1 Introduction -- 2 Challenges of Multi-Echelon Inventory Management from an Optimization Perspective -- 3 Literature Review of Inventory Management -- 4 Reinforcement Learning for Inventory Management -- 4.1 Markov (Decision) Processes -- 5 Introduction to Reinforcement Learning -- 5.1 Value-Based Methods -- 5.2 Policy-Based Methods -- 5.3 Actor-Critic Methods -- 6 Evaluation -- 7 Discussion of Results -- 8 Outlook -- 9 Conclusions -- 10 Acronyms -- References -- *-1pc Specialized Quantitative Tools in the Life Science Industry -- An Invitation to Stochastic Differential Equations in Healthcare -- 1 Introduction -- 1.1 Brownian Motions -- 1.2 Ito's Integral and Solutions of Geometric Brownian Motions (GBM) -- 1.3 Existence of Solutions of Stochastic Differential Equations -- 2 Numerical Methods for SDEs -- 2.1 Euler-Maruyama Method -- 2.2 -Maruyama Methods -- 2.3 Stochastic Runge-Kutta Methods -- 3 A Numerical Evidence on PK/PD Models. |
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| Formatted contents note |
References -- Life Events that Cascade: An Excursion into DALY Computations -- 1 Introduction -- 2 The Hawkes-Cox Framework -- 2.1 The Choice of Kernel and the R�ole of (Se(B -- 3 Dynkin's Formula -- 4 Theoretical Moments -- 4.1 The Moments of Counts in an Interval -- 4.2 The Covariance -- 5 Learning and Optimization -- 6 Synthetic Experiments -- 6.1 Calibration -- 7 Disability Adjusted Life Years -- 8 Concluding Remarks -- References. |
| 588 ## - |
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| -- |
Description based on publisher supplied metadata and other sources. |
| 590 ## - LOCAL NOTE (RLIN) |
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| Local note |
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2023. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries. |
| 655 #4 - INDEX TERM--GENRE/FORM |
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| Genre/form data or focus term |
Electronic books. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Mekler, Philipp. |
|
|---|
| Personal name |
Mu, Gang. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
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| Display text |
Print version: |
| Main entry heading |
Canci, Jung Kyu |
| Title |
Quantitative Models in Life Science Business |
| Place, publisher, and date of publication |
Cham : Springer International Publishing AG,c2022 |
| International Standard Book Number |
9783031118135 |
| 797 2# - LOCAL ADDED ENTRY--CORPORATE NAME (RLIN) |
|---|
| Corporate name or jurisdiction name as entry element |
ProQuest (Firm) |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
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| Uniform title |
SpringerBriefs in Economics Series |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
https://ebookcentral.proquest.com/lib/kliuc-ebooks/detail.action?docID=7141534 |
| Public note |
Click to View |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
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| Koha item type |
E-book |
